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Emergence of antibiotics resistant bacteria by horizontal gene transfer

​Bacteriology​, Laboratory of Microbiology

University of Tsukuba

Overview

We are studying evolutionary/adaptation strategies of Gram-positive pathogens. Major research interests include population heterogeneity, and the acquisition of antibiotic resistance. The main research target is the important human pathogen Staphylococcus aureus that inhabits in our nasal cavity but can cause a variety of diseases.

 

Staphylococcus aureus is a commensal bacterium that naturally inhabits the nasal cavity of mammals, but it is also an opportunistic pathogen responsible for a broad spectrum of infections ranging from food poisoning and superficial skin abscesses to more serious diseases such as pneumonia, meningitis, osteomyelitis, septicemia and toxic shock syndrome. It has acquired resistance to a wide variety of antibiotics, and methicillin-resistant strains (MRSA), the most common cause of nosocomial infections, are now spreading into the community. We are studying evolutionary/adaptation strategies of S. aurus, from our original view points.

In this course you will learn about Emergence of antibiotics resistant bacteria by horizontal gene transfer.

​We are sure you'll this find this course challenging and interesting.

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English Task

Please download the PDF document here. Print it out. There are three parts. Please do the first part before watching the video below, the second part is to be done during the video, and the third part after finishing the video and task. In the first part it asks you to write Japanese translations of English words, but if you are not Japanese, please do this in your first language. Upon completion of the exercise, please scan/photograph your work and email to: mayers@md.tsukuba.ac.jp (Thomas Mayers)

English Japanese Dictionary

Methodology to study the horizontal transmission of DNA in Staphylococcs aureus 

Watch the video

Your Task

Please download the Word document here, carefully read the questions and write your responses. You can re-watch the videos as many times as you like. You can do extra research by downloading the research papers below and searching for information on the Internet. Responses must be typed. Upon completion of the exercise, please email to: mayers@md.tsukuba.ac.jp (Thomas Mayers)

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